Tag Archive for life sciences
Berkeley Lab Researchers Discover How and Where Breast Tumor Cells Become Dormant and What Causes Them to Become Metastatic
Berkeley Lab researchers have identified the microenvironment surrounding microvasculature as a niche where dormant breast cancer cells may reside, and the sprouting of microvasculature blood vessels as the event that transforms dormant cancer cells into metastatic tumors.
Berkeley Lab Discoveries Open New Hope for MMP Cancer Therapies
New evidence supports earlier findings that cancer therapy drugs based on a family of enzymes called metalloproteinases (MMPs) failed in clinical trials because they were aimed at the wrong target.
Revealing the Secrets of Motility in Archaea
The protein structure of the archaellum, the motor that propels many species of Archaea, the third domain of life, has been characterized for the first time by a team from Berkeley Lab and the Max Planck Institute for Terrestrial Microbiology. A ring made of six identical proteins derives energy from hydrolyzing adenosine triphosate (ATP) and uses this energy to drive shape changes, both assembling and rotating the archaellum’s whiplike propeller.
New Computational Pipeline Analyzes Tumor Images, May Help Predict Response to Cancer Therapy
How’s this for big data: A whole-slide image of a tumor section can be ten billion pixels. There can be thousands of such images in the tumor cohorts maintained by The Cancer Genome Atlas project, which are collected from a large pool of patients.
The images are a potential treasure trove for the emerging field of [...]
Berkeley Lab Scientists Help Map Molecular Architecture of Organelle Critical to Hearing
To learn how something works in biology, it pays to start really small. Take this research for example: A team that includes Berkeley Lab scientists has identified and mapped the locations of many of the proteins that compose a hair bundle, which is an organelle that sprouts from hair cells in the inner ear.
Their work [...]
Medical imaging goes underground: SPECT maps 3-D changes in soil samples, may shed light on bioremediation
The same medical imaging technology that doctors use to noninvasively image the heart and brain is now giving scientists a close-up view of the subsurface world. Berkeley Lab scientists are developing a way to use Single Photon Emission Computed Tomography, or SPECT, to map 3-D changes in sediment samples without disturbing them.
Their work could help [...]
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